Multiscale Modeling of the Ventricles: From Cellular Electrophysiology to Body Surface Electrocardiograms

• Tác giả: David Urs Josef Keller
• Ngôn ngữ: eng
• ISBN-13: 978-3866447141
• ISBN: KSP/1000023886
• Ký hiệu phân loại: 616.12075470113 Diseases of cardiovascular system
• Thông tin xuất bản: Karlsruhe : KIT Scientific Publishing, 2011
• Mô tả vật lý: 1 electronic resource (XIII, 248 p. p.)
• Bộ sưu tập: Tài liệu truy cập mở
• ID: 202990

Tóm tắt

This work is focused on different aspects within the loop of multiscale modeling:On the cellular level, effects of adrenergic regulation and the Long-QT syndrome have been investigated.On the organ level, a model for the excitation conduction system was developed and the role of electrophysiological heterogeneities was analyzed.On the torso level a dynamic model of a deforming heart was created and the effects of tissue conductivities on the solution of the forward problem were evaluated.