B-Vitamins and One-Carbon Metabolism

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Tác giả: Kristina Pentieva (Ed.)

Ngôn ngữ: eng

ISBN-13: 978-3038429739

Ký hiệu phân loại:

Thông tin xuất bản: Basel, Switzerland : MDPI - Multidisciplinary Digital Publishing Institute, 2018

Mô tả vật lý: 1 electronic resource (XII, 390 p.)

Bộ sưu tập: Tài liệu truy cập mở

ID: 228630

 Folate, vitamin B12, vitamin B6 and riboflavin play a key role as coenzymes in one-carbon metabolism which, in turn, is essential for a broad range of fundamental physiological processes, including RNA and DNA synthesis, cell division, tissue growth and methylation. Deficiencies or imbalance of B-vitamins, as well as genetic polymorphisms and environmental factors, are shown to disturb the normal function of one-carbon metabolism with adverse effects on human health. Although a vast volume of research has already been conducted in this area, there are still significant gaps in our knowledge that require further investigations. This Special Issue of Nutrients invited submission of manuscripts, original research or reviews of the scientific literature, focused on novel findings in relation to B-vitamins and one-carbon metabolism in terms of: metabolic roles and molecular mechanisms
  gene-nutrient interactions
  fetal growth and programing
  risk of disease (birth defects and pregnancy related conditions, cancer, cardiovascular disease and hypertension, neuropsychiatric disease, osteoporosis)
  health effects of B-vitamin supplementation and food fortification.
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