Imaging biomarkers in neurodegeneration [electronic resource] : current and future practices

• Ngôn ngữ: eng
• Ký hiệu phân loại: 612.8 Nervous system Sensory functions
• Thông tin xuất bản: Washington, D.C. : Oak Ridge, Tenn. : United States. Dept. of Energy. Office of Science ; Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy, 2020
• Mô tả vật lý: Size: Article No. 49 : , digital, PDF file.
• Bộ sưu tập: Metadata
• ID: 259872
• Chủ đề: 1. 60 applied life sciences; 2. Alzheimer?s disease; 3. Dementia; 4. Machine learning; 5. Mri; 6. Neurodegenerative diseases; 7. Neuroimaging; 8. Pet

Tóm tắt

There is an increasing role for biological markers (biomarkers) in the understanding and diagnosis of neurodegenerative disorders. The application of imaging biomarkers specifically for the in vivo investigation of neurodegenerative disorders has increased substantially over the past decades and continues to provide further benefits both to the diagnosis and understanding of these diseases. This review forms part of a series of articles which stem from the University College London/University of Gothenburg course ?Biomarkers in neurodegenerative diseases?. In this review, we focus on neuroimaging, specifically positron emission tomography (PET) and magnetic resonance imaging (MRI), giving an overview of the current established practices clinically and in research as well as new techniques being developed. We will also discuss the use of machine learning (ML) techniques within these fields to provide additional insights to early diagnosis and multimodal analysis.