Positron emission tomography probe to monitor selected sugar metabolism in vivo [electronic resource]

• Ngôn ngữ: eng
• Ký hiệu phân loại: 611.018 Cytology and histology
• Thông tin xuất bản: Oak Ridge, Tenn. : Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy, 2017
• Mô tả vật lý: Medium: ED : , digital, PDF file.
• Bộ sưu tập: Metadata
• ID: 260851
• Chủ đề: 1. 47 other instrumentation; 2. 59 basic biological sciences; 3. 60 applied life sciences

Tóm tắt

The invention disclosed herein discloses selected ribose isomers that are useful as PET probes (e.g. [18F]-2-fluoro-2-deoxy-arabinose). These PET probes are useful, for example, in methods designed to monitor physiological processes including ribose metabolism and/or to selectively observe certain tissue/organs in vivo. The invention disclosed herein further provides methods for making and using such probes.