Breast cancer is the most frequently diagnosed cancer in U.S. women and prostate cancer is the second leading cause of cancer death in American men. X-ray mammography is the principal breastcancer screening tool available, but its false positive rate is more than 80%. Prostate-specific antigen (PSA) screening, which measures the level of PSA in a man?s blood, is no longer recommended by the U.S. task force for prostate-cancer screening. Los Alamos National Security (LANS) has developed novel imaging technologies for early-stage cancer detection based on advanced ultrasonic analyses. In particular, Los Alamos has developed ultrasoundwaveform tomography and related super-resolution ultrasound- imaging technologies that can provide significantly improved image resolution and characterization of early-stage cancers and thus potentially save lives.