Pnp gene modification for improved xylose utilization in Zymomonas [electronic resource]

• Ngôn ngữ: eng
• Ký hiệu phân loại: 666.3 Pottery
• Thông tin xuất bản: Oak Ridge, Tenn. : Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy, 2014
• Mô tả vật lý: Medium: ED : , digital, PDF file.
• Bộ sưu tập: Metadata
• ID: 263795
• Chủ đề: 1. 09 biomass fuels; 2. 59 basic biological sciences

Tóm tắt

The endogenous pnp gene encoding polynucleotide phosphorylase in the Zymomonas genome was identified as a target for modification to provide improved xylose utilizing cells for ethanol production. The cells are in addition genetically modified to have increased expression of ribose-5-phosphate isomerase (RPI) activity, as compared to cells without this genetic modification, and are not limited in xylose isomerase activity in the absence of the pnp modification.