The water-energy nexus is an important issue in regards to U.S. energy security and its significance will increase in the future due to increasing populations, energy demand, and competition for available water. The subsurface storage of carbon dioxide (along with fossil energy resource extraction), could generate significant quantities of brine, which if effectively treated could be beneficially reutilized. This document reports results from U.S. Department of Energy Project DE-FE0026315 which evaluated the use of electrocoagulation (EC) and supercritical water (SCW) treatment as a means to generate a water product for beneficial reuse from brine. The use of a novel SCW treatment system was studied with simulated and field-derived brine fluids. In addition, selective removal of high-value brine components via EC was studied. Techno-economics for treatment of high dissolved solids content brine (180,000 ppm) is also reported.