Pathogenicity Islands and the Evolution of Pathogenic Microbes [electronic resource] : Volume I

• Tác giả: J Hacker, J.B Kaper
• ISBN-13: 978-3642560316
• Ký hiệu phân loại: 616.9041 Other diseases
• Thông tin xuất bản: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2002.
• Mô tả vật lý: XXXIV, 444 p. , online resource.
• Bộ sưu tập: Metadata2
• ID: 288568
• Chủ đề: 1. Medical genetics; 2. Medical microbiology; 3. Medical Microbiology; 4. Medical Genetics

Tóm tắt

It has been known for a number of years that not only pathogenicity islands but also plasmids and bacteriophages are able to carry genes whose products are involved in pathogenic processes. Accordingly, such elements and their products play an important role in pathogenesis due to the intestinal E. coli as well to Shigellae. Another interesting aspect which is reflected in different articles is that genomes evolve by acquisition of new pieces of DNA following gene transfer, but also by genome reduction. Different mechanisms include the deletion of sequences or the elimination of functions by the accumulation of point mutations or rearrangements.