Mucosal Delivery of Drugs and Biologics in Nanoparticles [electronic resource]

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Tác giả: Nitesh K Kunda, Pavan Muttil

Ngôn ngữ: eng

ISBN-13: 978-3030359102

Ký hiệu phân loại: 615.19 Pharmaceutical chemistry

Thông tin xuất bản: Cham : Springer International Publishing : Imprint: Springer, 2020.

Mô tả vật lý: VIII, 277 p. 52 illus., 42 illus. in color. , online resource.

Bộ sưu tập: Metadata2

ID: 296154

 This book focuses on the application of nanotechnology to deliver drugs and biological agents by the mucosal routes of administration i.e. nasal, pulmonary, buccal, and oral routes.It provides an overview of nanotechnology in drug delivery with a description of different types of nanoparticles, methods of preparation and characterization, and functionalization for site-specific drug delivery. Mucosal Delivery of Drugs and Biologics in Nanoparticles emphasize the use of nanoparticles in treating various cancers and infectious diseases. It broadens the use of nanoparticles by including biologics, including vaccines and immunotherapies, apart from drugs. It acknowledges the concerns around the potential toxicity of nanoparticles to the host
  few chapters will discuss the biodistribution of these nanoparticles when mucosal routes of administration are employed. Further, the interaction of nanoparticles with the host's immune cells is discussed. Moreover,it reviews the regulatory aspects of nanotechnology in product development, especially when delivered by the mucosal route of administration. Lastly, discusses the challenges and opportunities to manufacture nanoparticles on an industrial scale. This book will be the first of its kind to focus on the design, development and delivery of nanoparticles when administered by different mucosal routes.
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