This Special Issue will focus on assistive technology (AT) to address biomechanical and control of movement issues in individuals with impaired health, whether as a result of disability, disease, or injury. All over the world, technologies are developed that make human life richer and more comfortable. However, there are people who are not able to benefit from these technologies. Research can include development of new assistive technology to promote more effective movement, the use of existing technology to assess and treat movement disorders, the use and effectiveness of virtual rehabilitation, or theoretical issues, such as modeling, which underlie the biomechanics or motor control of movement disorders. This Special Issue will also cover Internet of Things (IoT) sensing technology and nursing care robot applications that can be applied to new assistive technologies. IoT includes data, more specifically gathering them efficiently and using them to enable intelligence, control, and new applications.