Molecular and Clinical Advances in Understanding Early Embryo Development

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Tác giả: Lon J van Winkle

Ngôn ngữ: eng

ISBN-13: 978-3036574929

ISBN-13: 978-3036574936

ISBN: books978-3-0365-7492-9

Ký hiệu phân loại:

Thông tin xuất bản: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023

Mô tả vật lý: 1 electronic resource (256 p.)

Bộ sưu tập: Tài liệu truy cập mở

ID: 377007

This reprint considers a wide variety of topics concerning molecular and clinical advances in understanding early mammalian embryo development. The authors of various chapters of this book examine oocyte biology, preimplantation embryo development, blastocyst implantation in the uterus, and second cellular lineage differentiation. In addition, epigenetic contributions to reproduction, which may occur throughout pregnancy and in resultant offspring, are also considered. Environmentally induced epigenetic changes in germ cells can render mammalian offspring less healthy, and these changes can be difficult to reverse. Included in these changes are those caused by assisted reproductive technologies (ARTs). It remains to be determined whether the healthiest preimplantation embryos develop in vitro in conditions that mimic the physiological environment in vivo or whether simpler conditions can also foster this development in vitro. In this regard, a number of advances as well as challenges in ART are considered by the authors of the chapters included in this book.
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