This textbook provides a toolbox, a guidebook, and an instruction manual for researchers and interventionists who want to conceptualize and study applied problems from a developmental systems perspective, and for those who want to teach their graduate (or advanced undergraduate) students how to do this. It is designed to be useful to practitioners who focus on applied developmental problems, such as improving the important developmental contexts where people live, learn, and work, including the applied professions in education, social work, counseling, health care, community development, and business, all of which at their core are concerned with optimizing the development of their students, clients, patients, workers, citizens, and others whose lives they touch.